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Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
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Internal Medicine Endocrinology

Endocrinology
17-05-2024 Acute Adrenal Insufficiency News

New guideline on glucocorticoid-induced adrenal insufficiency

Read more

The European Society of Endocrinology and the Endocrine Society have published a joint guideline on glucocorticoid-induced adrenal insufficiency.

Editor's Choice

Understanding the new EMA guideline on medicinal products for diabetes

Diabetes Therapy Guideline at a Glance

An overview of the revised European Medicines Agency guideline on the clinical investigation of medicinal products for the treatment or prevention of type 1 and 2 diabetes.

Hyalinizing trabecular tumor of the thyroid

Open Access Thyroid Cancer Case Study

Imaging, cytologic, histologic, and molecular investigations all contributed to the diagnosis of a rare case of HTT in a woman with an incidentally discovered mass in the left lobe of her thyroid gland.

Using tirzepatide in clinical practice

Open Access Type 2 Diabetes Review

Practical advice on how to use tirzepatide in the management of type 2 diabetes, according to the clinical profile and therapeutic goals. Learn about adverse events, special warnings, precautions, and more.

Melatonin supplements not linked to risk for type 2 diabetes and CVD

13-05-2024 Type 2 Diabetes News

Self-reported use of melatonin supplements is not linked to the risk for type 2 diabetes or CVD, but regular use may lessen the risk of CVD associated with long-term night shift work.

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Latest News

New guideline on glucocorticoid-induced adrenal insufficiency

17-05-2024 Acute Adrenal Insufficiency News

Fezolinetant offers vasomotor symptom relief in menopause

16-05-2024 Climacterium and Menopause News

Breathe easy — GLP-1 receptor agonist use not associated with post-op respiratory complications

15-05-2024 Type 2 Diabetes News

Melatonin supplements not linked to risk for type 2 diabetes and CVD

13-05-2024 Type 2 Diabetes News

Hybrid closed loop system shows some benefits in pregnant women

10-05-2024 Diabetes and Pregnancy News

Setmelanotide a potential treatment for hypothalamic obesity

08-05-2024 Hypothalamic Disease News
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Case Studies

Hyalinizing trabecular tumor of the thyroid

Open Access Thyroid Cancer Case Study

Imaging, cytologic, histologic, and molecular investigations all contributed to the diagnosis of a rare case of HTT in a woman with an incidentally discovered mass in the left lobe of her thyroid gland.

An unusual complication of hemorrhagic fever with renal syndrome

Open Access Hypopituitarism Case Study

Partial hypopituitarism with adrenocorticotropin deficiency as the main manifestation in a man who presented with fatigue, nausea, poor appetite, and a history of HFRS.

Managing exogenous insulin antibody syndrome

Open Access Type 1 Diabetes Case Study

EIAS can cause hyperglycemia, hypoglycemia, and ketoacidosis in people with diabetes. This case in an older adult with type 1 diabetes shows how EIAS can be managed in an outpatient setting.
Type 2 Diabetes Podcast

Using CGM to optimize type 2 diabetes management with non-intensive insulin treatment in primary care

Listen now

With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report. 

Supported by: Abbott Diabetes Care

Prof. Samuel Seidu
Developed by: Adis

Current Reviews

Sarcopenic Obesity and Cardiovascular Disease: An Overlooked but High-Risk Syndrome

Open Access Obesity Review

In an era marked by a global obesity epidemic and an aging population, the interplay of obesity and age-related changes has emerged as a critical public health concern. Obesity is widely recognized as a significant risk factor for cardiometabolic …

The interlink between thyroid autoimmunity and type 1 diabetes and the impact on male and female fertility

Type 1 Diabetes Review Article

The aim of this review is to discuss the several interconnections between thyroid autoimmunity and type 1 diabetes in terms of epidemiology, immunoserology, genetic predisposition, and pathogenic mechanisms. We will also analyze the impact of …

Safety and efficacy of GLP-1 and glucagon receptor dual agonist for the treatment of type 2 diabetes and obesity: a systematic review and meta-analysis of randomized controlled trials

Obesity Review

The escalating prevalence of type 2 diabetes mellitus (T2DM) has become a pressing public health issue, with projections indicating a substantial increase in diagnosed cases over the next two decades [ 1 ]. Similarly, the World Health Organization …

Obesity and Esophageal Dysfunction

Gastroesophageal Reflux Disease

Obesity is now the most common chronic disease in the world, with more than 1 billion people affected worldwide [ 1 ]. It is projected that by 2030, 1 in 2 persons will meet criteria for obesity and 1 in 4 persons for severe obesity in the United …
Type 1 Diabetes Podcast

Episode 10: Disease-modifying therapy for type 1 diabetes

Listen now

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu
Insulins Clinical Trial Summary

At a glance: The ONWARDS insulin icodec trials

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A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.

Developed by: Springer Medicine

Editor's Choice | Endocrinology Journals

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CME & eLearning

Expert Interviews | Videos (Link opens in a new window)

Pediatric Obesity

With adolescent obesity at an all-time high, greater understanding of the individual cost and societal burden is crucial. Discover the unique challenges faced by adolescents with obesity, and learn effective strategies to help young people to overcome this disease.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

Diabetes

1.5 AMA PRA Category 1 Credit(s)™

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Vodcasts | Case Scenarios (Link opens in a new window)

Type 2 Diabetes

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Further Reading

Germline polymorphisms of the NOD2 pathway may predict the effectiveness of radioiodine in differentiated thyroid cancer treatment

Open Access Thyroid Cancer Original Article

Differentiated thyroid cancer (DTC) is the prevailing endocrine malignancy [ 1 ] and is predominantly treated with surgery and radioiodine [ 2 ]. Despite its generally promising clinical trajectory, patients presenting with distant metastases …

Plant-based diet adherence is associated with metabolic health status in adults living with and without obesity

Open Access Obesity Original Contribution

The prevalence of obesity has tripled worldwide over the last 40 years, representing a major public health issue, and it is estimated that more than one billion people will be living with obesity by 2030 [ 1 ]. Obesity is a complex and …

The interplay between excess weight and hyper-glycemia on NCDs in Italy: results from a cross-sectional study

Open Access Overweight Original Article

The continuing growth in the prevalence of overweight and obesity is a cause of serious concern in all regions of the world, and the phenomenon is increasingly taking the form of a global pandemic. In 2015, a total of 603.7 million adults were …

An analysis of the association between breast density and body mass index with breast cancer molecular subtypes in early breast cancer: data from a Spanish population

Open Access Breast Cancer RESEARCH ARTICLE

Breast cancer continues to be an important health problem and is one of the most common causes of cancer deaths in women worldwide, with an estimated 358,967 new cases and 90,665 breast cancer-related deaths in the European Union annually [ 1 ].

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17-05-2024 Acute Adrenal Insufficiency News

New guideline on glucocorticoid-induced adrenal insufficiency

The European Society of Endocrinology and the Endocrine Society have published a joint guideline on glucocorticoid-induced adrenal insufficiency.

Read more

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Risk of autoimmune disease linked to remission of Cushing’s disease after surgery

05-03-2024 Cushing's Syndrome News

Autoimmune comorbidity common in young people with type 1 diabetes

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Best-practice advisory boosts primary aldosteronism screening rates

22-01-2024 Hyperaldosteronism News

Bilateral co-secretory lesions, coexisting Cushing syndrome and primary aldosteronism

Open Access Cushing's Syndrome Case Study
Open Access Progesterone Review

Oral micronized progesterone for diagnosis and therapy

Micronized progesterone can be used for the diagnosis and therapy of various endocrine conditions, from amenorrhea to premenstrual syndrome, PCOS, perimenopause, and menopause.

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Highlights from EndoBridge 2023

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Impact of PCOS on quality of life

Open Access Polycystic Ovary Syndrome Review

Predictors of CHH reversal identified

19-03-2024 Hypogonadism News

Turner syndrome: improving the transition from pediatric to adult care

Open Access Turner's Syndrome Review

HNF1A gene mutations and primary ovarian failure

Open Access Primary Ovarian Insufficiency Case Study
Open Access Type 2 Diabetes Review

Using tirzepatide in clinical practice

Practical advice on how to use tirzepatide in the management of type 2 diabetes, according to the clinical profile and therapeutic goals. Learn about adverse events, special warnings, precautions, and more.

Read more

Improving outcomes in peripheral artery disease

Free for a limited time Peripheral Arterial Disease Review

Setmelanotide a potential treatment for hypothalamic obesity

08-05-2024 Hypothalamic Disease News

A new consideration in HF and obesity

Open Access Heart Failure Review

Managing exogenous insulin antibody syndrome

Open Access Type 1 Diabetes Case Study

GLP-1 receptor agonists not associated with increased risk for thyroid cancer

02-05-2024 Incretin Mimetics News
Open Access Thyroid Cancer Case Study

Hyalinizing trabecular tumor of the thyroid

Imaging, cytologic, histologic, and molecular investigations all contributed to the diagnosis of a rare case of HTT in a woman with an incidentally discovered mass in the left lobe of her thyroid gland.

Read more

GLP-1 receptor agonists not associated with increased risk for thyroid cancer

02-05-2024 Incretin Mimetics News

Dilated cardiomyopathy due to hypocalcemia

Open Access Cardiomyopathy Case Study

Does thyroid scintigraphy still have a role in evaluating thyroid nodules?

Open Access Thyroid Disease Review

Type D personality common in hypothyroidism

26-04-2024 Hypothyroidism News

Highlights from EndoBridge 2023

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