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08-05-2024 Hypothalamic Disease News

Setmelanotide a potential treatment for hypothalamic obesity

Setmelanotide has been shown to achieve clinically meaningful reductions in bodyweight and hunger among people with hypothalamic obesity.

Editor's Choice

A new consideration in HF and obesity

Open Access Heart Failure Review

Heart failure and obesity frequently co-present. Learn why you should measure epicardial adiposity thickness in your HFpEF patients with elevated BMI.

Highlights from EndoBridge 2023

Free for a limited time Endocrinology Review

Everything you need to know from EndoBridge 2023. Find out the latest developments across all aspects of endocrinology and metabolism, and learn about the clinical approaches to common endocrine issues.

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

STEP-HFpEF trial findings indicate that weekly semaglutide improves heart failure symptoms, physical limitations, and body weight in people with obesity-related heart failure and type 2 diabetes.

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Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Case Studies

Spontaneous remission of diabetes in a girl with systemic lupus erythematosus

Open Access Diabetes Case Study

A unique, reversible diabetes subtype, suggestive of an autoimmune origin, in a 14-year-old girl with obesity and SLE, who presented with ketoacidosis, elevated HbA1c and positive anti-insulin antibodies.

Restoring normal food passage in a patient with severe post-bariatric hypoglycemia

Open Access Bariatric Surgery Case Study

Successful laparoscopic reversal of RYGB in a patient who had undergone many bariatric revision surgeries and was experiencing severe, unresponsive post-bariatric hypoglycemia and daily neuroglycopenic seizures.

Current Reviews

Sarcopenic Obesity and Cardiovascular Disease: An Overlooked but High-Risk Syndrome

Open Access Obesity Review

In an era marked by a global obesity epidemic and an aging population, the interplay of obesity and age-related changes has emerged as a critical public health concern. Obesity is widely recognized as a significant risk factor for cardiometabolic …

Safety and efficacy of GLP-1 and glucagon receptor dual agonist for the treatment of type 2 diabetes and obesity: a systematic review and meta-analysis of randomized controlled trials

Obesity Review

The escalating prevalence of type 2 diabetes mellitus (T2DM) has become a pressing public health issue, with projections indicating a substantial increase in diagnosed cases over the next two decades [ 1 ]. Similarly, the World Health Organization …

Obesity and Esophageal Dysfunction

Obesity is now the most common chronic disease in the world, with more than 1 billion people affected worldwide [ 1 ]. It is projected that by 2030, 1 in 2 persons will meet criteria for obesity and 1 in 4 persons for severe obesity in the United …

Cardiovascular Benefits of GLP-1 Receptor Agonists in Patients Living with Obesity or Overweight: A Meta-analysis of Randomized Controlled Trials

Obesity Systematic Review

Obesity is a multifaceted condition, with an increasing incidence and prevalence worldwide [ 1 ]. Treatment options for obesity are currently limited, and the condition is associated with a higher risk of dyslipidemia, type 2 diabetes mellitus …

Webinar | 08-11-2023 | 18:00 (CET)

Keynote webinar | Spotlight on diet and diabetes

An expert-led symposium exploring the prevention and management of type 2 diabetes through dietary interventions. Highlights include discussion of the recent EASD guidelines, therapeutic diets, food types and processing, plus psychological factors that influence patient success, and the drivers of healthy eating and diabetes control.

Prof. Mike Lean
Prof. Falko Sniehotta
Developed by: Springer Medicine

Expert Interviews | Videos (Link opens in a new window)

With adolescent obesity at an all-time high, greater understanding of the individual cost and societal burden is crucial. Discover the unique challenges faced by adolescents with obesity, and learn effective strategies to help young people to overcome this disease.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Further Reading

Plant-based diet adherence is associated with metabolic health status in adults living with and without obesity

Open Access Obesity Original Contribution

The prevalence of obesity has tripled worldwide over the last 40 years, representing a major public health issue, and it is estimated that more than one billion people will be living with obesity by 2030 [ 1 ]. Obesity is a complex and …

The interplay between excess weight and hyper-glycemia on NCDs in Italy: results from a cross-sectional study

Open Access Overweight Original Article

The continuing growth in the prevalence of overweight and obesity is a cause of serious concern in all regions of the world, and the phenomenon is increasingly taking the form of a global pandemic. In 2015, a total of 603.7 million adults were …

An analysis of the association between breast density and body mass index with breast cancer molecular subtypes in early breast cancer: data from a Spanish population

Open Access Breast Cancer RESEARCH ARTICLE

Breast cancer continues to be an important health problem and is one of the most common causes of cancer deaths in women worldwide, with an estimated 358,967 new cases and 90,665 breast cancer-related deaths in the European Union annually [ 1 ].

Factors Influencing Referral for Bariatric Surgery by Primary Care Physicians in Northern Israel

Open Access Bariatric Surgery Original Contributions

The worldwide prevalence of obesity has nearly tripled since 1975, in 2016, about 13% of the world’s adult population were obese [ 1 ]. Obesity is related to multiple comorbidities, including diabetes mellitus, cardiovascular disease, hypertension …