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41857 search results for:

Diabetes and Cardiac Diseases 

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  1. 05-09-2023 | Heart Failure | ReviewPaper

    Cardiac Metabolism, Reprogramming, and Diseases

    Cardiovascular diseases (CVD) are the leading cause of global mortalities with a growing epidemic, imposing a heavy burden on the economy and healthcare system [ 1 – 3 ]. Despite pioneering achievements in the identification of key mechanisms …

  2. 28-10-2023 | Chronic Kidney Disease | OriginalPaper

    Urinary cadmium was linearly and positively associated with cardiac infarction/injury score and subclinical myocardial injury in the general population without cardiovascular diseases and chronic kidney disease

    Cardiovascular diseases (CVDs), which mainly include ischemic heart disease and stroke, are the leading cause of disability and death worldwide. In the past 30 years, the total number of patients with CVDs has increased from 271 million in 1990 to …

  3. Open Access 01-12-2023 | Echocardiography | OriginalPaper

    Spectrum of cardiac diseases among young and older adults defined by echocardiography at Jakaya Kikwete Cardiac Institute: A prospective cross-sectional study

    Worldwide, cardiovascular diseases (CVDs) remain an important cause of morbidity and mortality, with data showing that about two thirds of deaths that occurred in 2019 were due to non-communicable diseases: mainly cardiovascular [ 1 ]. Available …

  4. 16-05-2023 | Cardiac Amyloidosis | ReviewPaper

    Feature tracking cardiac magnetic resonance imaging to assess cardiac manifestations of systemic diseases

    Feature-tracking cardiac magnetic resonance (FT-CMR), with the ability to quantify myocardial deformation, has a unique role in the evaluation of subclinical myocardial abnormalities. This review aimed to evaluate the clinical use of cardiac

  5. 20-07-2022 | Myotonic Dystrophy | ReviewPaper

    Neuromuscular diseases and their cardiac manifestations under the spectrum of cardiovascular imaging

    Neuromuscular diseases (NMDs) include a broad spectrum of disorders that affect motor unit in every possible site, extending from the cell body of peripheral nerves to the muscle. The different lesion sites make this group of inherited disorders …

  6. 04-05-2024 | Diabetes Therapy | Guideline at a Glance

    New guideline of the European Medicines Agency (EMA) on the clinical investigation of medicinal products in the treatment and prevention of diabetes mellitus

    An overview of the revised European Medicines Agency guideline on the clinical investigation of medicinal products for the treatment or prevention of type 1 and 2 diabetes.

  7. 13-05-2024 | Type 2 Diabetes | News | Article

    Melatonin supplements not linked to risk for type 2 diabetes and CVD

    Self-reported use of melatonin supplements is not linked to the risk for type 2 diabetes or CVD, but regular use may lessen the risk of CVD associated with long-term night shift work.

  8. Open Access 16-04-2024 | Type 2 Diabetes | Review

    Prevention and treatment of ischaemic and haemorrhagic stroke in people with diabetes mellitus: a focus on glucose control and comorbidities

    The risks of ischemic and hemorrhagic stroke and poor neurological outcomes after stroke are increased in people with type 2 diabetes. Explore how to manage the hyperacute stroke stage and prevent CV disease.

  9. Open Access 01-12-2024 | Canagliflozin | ReviewPaper

    Research advances in the anti-inflammatory effects of SGLT inhibitors in type 2 diabetes mellitus

    Diabetes mellitus is one of the most significant global burden diseases. It is well established that a chronic, systemic, low-grade inflammatory condition is strongly correlated with type 2 diabetes mellitus (T2D) and the development of …

  10. Open Access 01-12-2024 | Aortic Dissection | OriginalPaper

    Diabetes and aortic dissection: unraveling the role of 3-hydroxybutyrate through mendelian randomization

    Aortic dissection is a severe cardiovascular condition characterized by the destabilization of the aortic wall [ 1 ], resulting in a sudden onset of symptoms such as severe pain radiating to the back and chest [ 2 ]. The acute phase of aortic …

  11. Open Access 01-12-2024 | OriginalPaper

    Prevalence of diabetic cardiomyopathy in patients with type 2 diabetes in a large academic medical center

    Diabetic cardiomyopathy (DbCM) is a primary myocardial disease with altered myocardial structure and fibrosis which results from diabetes-associated metabolic alterations [ 1 – 5 ]. DbCM is an asymptomatic stage B of heart failure (SBHF) in …

  12. 02-04-2024 | Prostate Cancer | ReviewPaper

    Understanding Cardiovascular Risk in Prostate Cancer: Role of Disparities, Diabetes, and Aging

    Prostate cancer (PC) and its intertwined relationship with cardiovascular disease (CVD) risk present a challenging paradigm for clinicians. It is vital to recognize that disparities in healthcare access and socioeconomic factors play a substantial …

  13. Open Access 01-12-2024 | Diabetes Prevention | OriginalPaper

    Effectiveness of artificial intelligence vs. human coaching in diabetes prevention: a study protocol for a randomized controlled trial

  14. Open Access 01-12-2024 | OriginalPaper

    Association between the triglyceride–glucose index and all-cause and CVD mortality in the young population with diabetes

    The incidence and mortality rates of cardiovascular diseases (CVDs) are on a steady rise, presenting a significant threat to both the global economy and human health. This surge in CVDs has emerged as a major public health challenge of global …

  15. 24-04-2023 | ReviewPaper

    Unmet Needs for Cardiac Rehabilitation in Africa: A Perennial Gap in the Management of Individuals with Cardiac Diseases

    Cardiac rehabilitation (CR) is a standard model of care, and an established component of comprehensive care that has been proven to reduce mortality and morbidity in patients with cardiac diseases. International clinical practice guidelines …

  16. Open Access 26-04-2024 | Type 1 Diabetes | OriginalPaper

    An Analysis of the Distribution of Direct Cost of Diabetes Care in Selected Districts in Italy

    Diabetes is a complex metabolic disorder with a higher risk of microvascular or macrovascular complications compared to the general population, which is associated with increased mortality [ 1 , 2 ]. In high-income countries, diabetes is one of the …

  17. Open Access 01-12-2024 | Diabetic Cardiomyopathy | OriginalPaper

    MAP4K4 exacerbates cardiac microvascular injury in diabetes by facilitating S-nitrosylation modification of Drp1

    Dynamin-related protein 1 (Drp1) is a crucial regulator of mitochondrial dynamics, the overactivation of which can lead to cardiovascular disease. Multiple distinct posttranscriptional modifications of Drp1 have been reported, among which …

  18. 25-04-2024 | Arterial Occlusive Disease | Online First

    Subclinical Atherosclerosis to Guide Treatment in Dyslipidemia and Diabetes Mellitus

    Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality in the USA. Atherosclerotic CVD (ASCVD) is the most common type of CVD and affects approximately 25 million US adults [ 1 , 2 ]. Dyslipidemia and type 2 diabetes

  19. Open Access 20-02-2024 | Dyslipidemia | Review

    Hyperlipidaemia in diabetes: are there particular considerations for next-generation therapies?

    Dyslipidemia is a major risk factor for CVD, especially in people with diabetes. New lipid-lowering treatments are being approved in this population, but what are their effects on glycemic control?

  20. Open Access 15-03-2024 | Type 2 Diabetes | OriginalPaper

    Circulating small extracellular vesicles mediate vascular hyperpermeability in diabetes

    Once considered a simplistic barrier between the blood and the vessel wall, the endothelium is now regarded as a dynamic and complex endocrine organ responsible for maintaining homeostasis across the vascular system [ 1 ]. Endothelial cells (ECs) …

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