Hypoxemia after treatment for acute type A aortic dissection can worsen the already poor prognosis. Cardiologists need to understand the risk factors and treatment strategies for managing this dangerous complication.
A person receiving a blood transfusion for severe anemia developed acute respiratory distress with hypoxia that resolved after treatment with steroids and supplemental oxygen.
Self-reported use of melatonin supplements is not linked to the risk for type 2 diabetes or CVD, but regular use may lessen the risk of CVD associated with long-term night shift work.
A review of prevention and treatment strategies for respiratory syncytial virus infection in older adults, with a special focus on the novel vaccines now available.
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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
A person receiving a blood transfusion for severe anemia developed acute respiratory distress with hypoxia that resolved after treatment with steroids and supplemental oxygen.
A patient with type II respiratory failure and pulmonary hypertension was diagnosed with RYR1-related myopathy, highlighting the importance of considering congenital myopathies in the differential diagnosis.
Next-generation sequencing is a powerful tool that can identify mutations or fusions in a wide range of cancers, enabling physicians to provide targeted therapy to patients and improve outcomes.
In this vodcast, Professor Andrew Beggs discusses practical aspects of this technique from the clinical viewpoint.
Supported by: Illumina, Inc., and Eli Lilly and Company
Open AccessCardiomyopathyEchocardiography (JM Gardin and AH Waller, Section Editors)
The prevalence of heart failure (HF) continues to grow globally with increasing financial burden worldwide. In 2017, there were 64.3 million people with HF globally [ 1 ] and 1.2 million HF admissions in the United States (US) alone [ 2 ]. The …
Inequitable access to care continues to hinder improvements in diagnosis and treatment of lung cancer. This review describes healthcare disparities in the changing landscape of non–small cell lung cancer (NSCLC) in the United States, focusing on …
Molecular profiling of circulating tumor DNA (ctDNA) to guide treatment decisions has found its way into routine management of patients with advanced cancer. This represents a pivotal advancement in precision oncology, offering a non-invasive and …
Sleep ApneaSleep Breathing Physiology and Disorders • Review
Obstructive sleep apnea(OSA) is a common sleep-related breathing disorder, with its prevalence being as high as 10% of the world population. Obstructive respiratory events, which are recurrent episodes of partial or total obstruction of the upper …
Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
A collaborative program highlighting the importance of molecular assessments and targeted treatment selection in people with biomarker-positive disease. Submit your questions for the experts now.
This expert-led infographic explains how to recognize and manage COPD exacerbations and explores the impact of these exacerbations at the patient and physician level.
Expert-led, multiformat program which will address the individualized management of NSCLC, through education on the detection of NTRK gene fusions, current evidence-based guidelines, and new and emerging therapies. Will also include guidance on integrating shared decision making into your clinical practice, drawing on insights from a patient on how best to communicate.
Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.
Open AccessSleep ApneaSleep Breathing Physiology and Disorders • Original Article
Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder. OSA can be characterised by partial or complete inspiratory upper airway collapse during sleep, resulting in periodic oxygen desaturation and disruption of sleep [ 1 …,
Open AccessCardiomyopathyEchocardiography (JM Gardin and AH Waller, Section Editors)
The prevalence of heart failure (HF) continues to grow globally with increasing financial burden worldwide. In 2017, there were 64.3 million people with HF globally [ 1 ] and 1.2 million HF admissions in the United States (US) alone [ 2 ]. The …
Pulmonary fibrosis is a clinical phenotype of various interstitial lung diseases (ILD) with differing etiologies [ 1 ]. Clinical trials in pulmonary fibrosis enroll patients based on clinical criteria in the absence of reliable molecular …
High-flow nasal cannula oxygen (HFNO) was primarily developed for neonatal intensive care. Over the years it found additional application in adults, mostly in intensive care units but also in severe trauma and other critically ill patients. Today …
Children with preschool wheeze experience a significantly greater reduction in wheeze severity 4 hours after treatment with the oral corticosteroid prednisolone versus placebo.
