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Melanoma 

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  1. Open Access 15-05-2024 | Melanoma | Online First

    SEOM-GEM clinical guidelines for cutaneous melanoma (2023)

    Cutaneous melanoma incidence is rising. Early diagnosis and treatment administration are key for increasing the chances of survival. For patients with locoregional advanced melanoma that can be treated with complete resection, adjuvant—and more …

  2. 16-05-2024 | Melanoma | Online First

    Access to melanoma drugs in Spain: a cross-sectional survey

  3. 01-07-2024 | Melanoma | ReviewPaper

    Malignant melanoma arising in a burn scar

    Secondary malignancies are rare but devastating complications of longstanding burn scars. Squamous cell carcinoma is the most common, followed by basal cell carcinoma and melanomas. There are fewer than 50 total reported cases of malignant …

  4. 01-07-2024 | Melanoma | Letter

    Occupational association with melanoma: a US ecological county-level analysis

  5. Open Access 01-12-2024 | Melanoma | OriginalPaper

    RICTOR/mTORC2 downregulation in BRAFV600E melanoma cells promotes resistance to BRAF/MEK inhibition

    Malignant melanoma is the deadliest form of skin cancer, and about 50% of tumors carry activating mutations (V600E/K) of the BRAF oncogene. In the clinics, BRAF V600E tumors can be selectively targeted by BRAF-inhibitors (BRAFi) administered in …

  6. Open Access 01-12-2024 | OriginalPaper

    Association of lipid-lowering drug targets with risk of cutaneous melanoma: a mendelian randomization study

    Cutaneous melanoma (CM), a life-threatening skin cancer, is responsible for 77% of all skin cancer-related deaths [ 1 , 2 ]. The incidence of CM is on the rise, increasing at an approximate rate of 3% annually [ 2 ]. Characterized by its high …

  7. Open Access 01-12-2024 | Choroidal Melanoma | OriginalPaper

    Construction of oxidative phosphorylation-related prognostic risk score model in uveal melanoma

    Uveal melanoma (UVM) is the predominant malignant intraocular tumor in adults [ 1 , 2 ]. Its incidence rate ranks first among intraocular tumors abroad and second only to retinoblastoma in China [ 3 – 5 ]. This highly malignant tumor exhibits a …

  8. 06-04-2024 | Basalioma | ReviewPaper

    Photodynamic application in diagnostic procedures and treatment of non-melanoma skin cancers

    Skin tumors commonly seen in dermatology are involved in all layers of the skin and appendages. While biopsy of affected skin remains an essential method to confirm diagnosis and to predicate tumor prognosis, it has its limitations. Recently …

  9. Open Access 01-05-2024 | Melanoma | OriginalPaper

    Preferences of physicians for treatment-related toxicity vs. recurrence in melanoma (GERMELATOX-A): the doctors’ perspective

    Over the years, significant advancements have been made in the treatment of melanoma, particularly with the introduction of targeted therapies and immunotherapies for patients with advanced melanoma (Garutti et al 2022 ). These treatments have been …

  10. Open Access 01-12-2024 | Melanoma | OriginalPaper

    Identification and characterization of a new potent inhibitor targeting CtBP1/BARS in melanoma cells

    Melanoma, a tumor that develops from an uncontrolled proliferation of melanocytes, is the most malignant form of skin cancer [ 1 – 4 ] and its worldwide incidence and mortality has been risen rapidly [ 5 – 7 ]. Melanoma contributes to more than 80% …

  11. Open Access 01-12-2024 | Choroidal Melanoma | OriginalPaper

    Modulating DNA damage response in uveal melanoma through embryonic stem cell microenvironment

    Uveal melanoma (UVM) is the most common primary intraocular malignancy in adults. As a highly aggressive form of ocular cancer originating in uveal melanocytes, it poses a significant threat to ocular vision and even causes cancer-related death.

  12. Open Access 27-03-2024 | Lymphedema | BriefCommunication

    ASO Author Reflections: Lymphoedema Related to Inguinal and Ilioinguinal Lymphadenectomy for Melanoma

    Lymphoedema is a feared side effect of lymphadenectomy, often resulting in chronic discomfort, infection, and reduced function in the affected individual. 1 Conflicting reports of the prevalence and severity of leg lymphoedema following inguinal …

  13. 29-04-2024 | Melanoma | Online First

    Bromodomain inhibition targeting BPTF in the treatment of melanoma and other solid tumors

    Epigenetic mechanisms have been shown to play an important role in the development of cancer. These include the activation of chromatin remodeling factors in various malignancies, including bromodomain plant homeodomain (PHD) finger transcription …

  14. Open Access 11-03-2024 | Melanoma | Online First

    RETRACTED ARTICLE: Cystoid Macular Oedema in a Patient Treated with STING Agonist and Ezabenlimab for Disseminated Melanoma

    The application of immunotherapy in managing advanced metastatic melanoma has markedly improved patient outcomes [ 1 ]. Even though the incidence of melanoma continues to rise [ 1 ], the median survival time for patients with advanced, inoperable …

  15. Open Access 01-12-2024 | Clear-Cell Sarcoma | OriginalPaper

    Navigating diagnostic challenges—distinguishing malignant melanoma and clear cell sarcoma of soft tissues: a case report and review of the literature

    In the context of encountering a melanocytic differentiated tumor, pathologists are confronted with the imperative task of discerning potential diagnoses, with clear cell sarcoma of soft tissues (CCSST) being among the considerations related to …

  16. 26-02-2024 | Melanoma | ReviewPaper

    Rapidly Evolving Pre- and Post-surgical Systemic Treatment of Melanoma

    With the development of effective BRAF-targeted and immune-checkpoint immunotherapies for metastatic melanoma, clinical trials are moving these treatments into earlier adjuvant and perioperative settings. BRAF-targeted therapy is a standard of …

  17. 14-05-2024 | Online First

    ASO Visual Abstract: Association Between Medicaid Expansion and Cutaneous Melanoma Diagnosis and Outcomes—Does Where You Live Make a Difference?

  18. Open Access 01-07-2024 | Melanoma | OriginalPaper

    Clinical outcomes of adjuvant nivolumab in resected stage III melanoma: comparison of CheckMate 238 trial and real-world data

    Systemic therapies indicated for patients with completely resected stage III or IV melanoma in the adjuvant setting include the immuno-oncology (I-O) agents nivolumab and pembrolizumab, as well as the BRAF plus MEK inhibitor combination of …

  19. 01-07-2024 | Cutaneous Squamous Cell Carcinoma | Letter

    Examining the association of non-melanoma skin cancer with immunomodulatory conditions: a cross-sectional analysis of the All of Us database

  20. 01-06-2024 | Melanoma | OriginalPaper

    Patient reported outcomes and patient experiences of immune checkpoint modulators for advanced or recurrent melanoma: a mixed methods study

    Nearly 66,000 people in the United States are living with advanced melanoma [ 1 ]. Survival rates have significantly improved since FDA approval of the first immune checkpoint modulator (ICM) therapy, ipilimumab, in 2011 [ 2 , 3 ]. The programmed …

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