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Radiotherapy 

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  1. Open Access 01-12-2024 | Radiotherapy | EditorialNotes

    Advances in personalized radiotherapy

    Radiotherapy is a mainstay of cancer treatment. The clinical response to radiotherapy is heterogeneous, from a complete response to early progression. Recent studies have explored the importance of patient characteristics in response to …

  2. 18-05-2024 | Online First

    Coping with modesty during radiotherapy for breast cancer: a multicentric study

    It is estimated that breast cancer accounted for 13.3% of all new cancer cases diagnosed in EU-27 countries in 2020 [ 1 ]. This makes it the most frequently occurring cancer, representing nearly 30% of all new diagnoses in women [ 1 ]. Recent …

  3. Open Access 08-05-2024 | Meningioma | Online First

    11C-Methionine uptake in meningiomas after stereotactic radiotherapy

    Meningiomas are the most encountered intracranial tumors [ 1 ]. Meningiomas at the skullbase or in close relation with large vascular structures, e.g., the venous sinuses, are challenging to treat. These patients often undergo multimodal treatment.

  4. 01-12-2024 | Craniopharyngioma | OriginalPaper

    Long-term outcomes of neuroendoscopic cyst partial resection combined with stereotactic radiotherapy for craniopharyngioma

    The first choice of treatment for craniopharyngioma is radical resection. In the past, craniotomy was the predominant surgical approach utilized to treat craniopharyngiomas, but a worldwide shift toward an extended transsphenoidal approach is in …

  5. 16-05-2024 | Dysphagia | Online First

    Dysphagia in Head and Neck Radiotherapy: The Influence of Pharyngeal Constrictor Anatomy and Dosimetry

    The goal of this study was to identify which anatomical and dosimetric changes correlated with late patient-reported dysphagia throughout the course of head and neck chemo-radiotherapy treatment. The patient cohort (n = 64) considered …

  6. Open Access 01-12-2024 | Systemic Therapy | OriginalPaper

    The therapeutic effect of radiotherapy combined with systemic therapy compared to radiotherapy alone in patients with simple brain metastasis after first-line treatment of limited-stage small cell lung cancer: a retrospective study

    Small cell lung cancer (SCLC) is a highly aggressive malignant tumor, accounting for approximately 15% of all lung cancers [ 1 ]. Although most SCLC patients have high sensitivity to initial chemotherapy (CT) and radiotherapy (RT), most patients …

  7. Open Access 01-12-2024 | Radiotherapy | OriginalPaper

    Carbon ion radiotherapy for mesonephric adenocarcinoma of the uterine cervix: a case report

    Cervical cancer causes more than 0.3 million deaths worldwide annually [ 1 ], and adenocarcinomas comprise approximately 25% of cervical cancers [ 2 ]. Mesonephric adenocarcinoma (MNA) is an extremely rare subtype that originates from the remnants …

  8. Open Access 19-05-2024 | Online First

    The impact of cancer patient pathway on timing of radiotherapy and survival: a cohort study in glioblastoma patients

    Glioblastoma (GBM) is an aggressive and incurable primary brain tumor; median overall survival (mOS) in unselected patients is approximately 12 months [ 1 , 2 ]. Treatment is multimodal; after surgery patients are scheduled for chemoradiotherapy.

  9. Open Access 01-12-2024 | Radiotherapy | Erratum

    Correction: Real world clinical experience using daily intelligence-assisted online adaptive radiotherapy for head and neck cancer

  10. Open Access 01-12-2024 | Radiotherapy | OriginalPaper

    Extracellular volume-based scoring system for tracking tumor progression in pancreatic cancer patients receiving intraoperative radiotherapy

    Approximately 30% of patients with locally advanced pancreatic cancer (LAPC) die of local progression [ 1 ], and only 11% of these patients could survive more than 3 years [ 2 ]. Therefore, improving the rate of local control and preventing local …

  11. Open Access 01-12-2024 | Cervical Cancer | OriginalPaper

    Efficacy and safety of different chemotherapy regimens concurrent with radiotherapy in the treatment of locally advanced cervical cancer

    Cervical cancer is the fourth most frequently diagnosed cancer and the fourth leading cause of cancer death in women, representing a major global health challenge. According to statistics, there are about 600,000 new cases of cervical cancer …

  12. Open Access 01-12-2024 | Metastasis | OriginalPaper

    FLASH radiotherapy for the treatment of symptomatic bone metastases in the thorax (FAST-02): protocol for a prospective study of a novel radiotherapy approach

    FLASH therapy is an emerging form of radiation therapy (RT) in which radiation is delivered at ultra-high dose rates of at least 40 Gy/s. Compared to RT given at conventional dose rates, FLASH RT has been shown in multiple animal models to cause …

  13. Open Access 01-12-2024 | Hepatocellular Carcinoma | OriginalPaper

    Microinvasion in hepatocellular carcinoma: predictive factor and application for definition of clinical target volume for radiotherapy

    Primary liver cancer is one of the most prevalent tumors that seriously threaten human health [ 1 ]. China is a prominent nation of liver cancer, as it encompasses approximately 50% of the worldwide total cases [ 2 ]. Hepatocellular carcinoma (HCC) …

  14. 01-06-2024 | Radiotherapy | OriginalPaper

    “Current”, “heated rods”, and “hot vapour”: why patients refuse radiotherapy as a treatment modality for cancer in northern Sri Lanka

    Radiotherapy is a curative treatment option for about 40% of cancers either alone or in combination with other modalities [ 1 ]. Despite robust evidence that radiotherapy improves clinical outcomes, a subset of patients with strong clinical …

  15. 08-03-2024 | Craniopharyngioma | ReviewPaper

    Fractionated stereotactic radiotherapy in craniopharyngiomas: A systematic review and single arm meta-analysis

    Craniopharyngiomas are rare benign neoplasms with an incidence of only 0.5 to 2 cases per million people per year, highlighting a bimodal age distribution: incidence rates in 5–19-year-olds and 50–74-year-olds, totaling 2% of all intracranial …

  16. Open Access 30-04-2024 | Hepatocellular Carcinoma | Online First

    Managing hepatocellular carcinoma across the stages: efficacy and outcomes of stereotactic body radiotherapy

    A retrospective study

    Liver cancer, ranking as the 6th most prevalent malignancy globally and standing as the third leading cause of cancer-related death, is a challenging malignancy and is surpassed only by lung and colorectal cancer [ 1 ]. Hepatocellular carcinoma …

  17. Open Access 01-12-2024 | Radiotherapy | OriginalPaper

    PErspective and current status of Radiotherapy Service in IRan (PERSIR)-1 study: assessment of current external beam radiotherapy facilities, staff and techniques compared to the international guidelines

    The number of new cancer cases was 19.3 million people worldwide in 2020, which is expected to reach 24.6 million in 2030, suggesting an increase of 27.5% [ 1 ]. Developing countries account for around 60% of all new cancer cases and 70% of all …

  18. Open Access 01-12-2024 | Hepatocellular Carcinoma | OriginalPaper

    Prognostic analysis of radiation-induced liver damage following carbon-ion radiotherapy for hepatocellular carcinoma

    External beam radiotherapy (EBRT) and stereotactic body radiotherapy (SBRT) are viable treatment options for patients with unresectable or inoperable hepatocellular carcinoma (HCC) [ 1 ]. Current guidelines suggest that SBRT is an advanced EBRT …

  19. 08-04-2024 | Radiotherapy | Erratum

    Correction: Tumor progression in tympanojugular paragangliomas: the role of radiotherapy and wait and scan

  20. Open Access 15-03-2024 | Brachytherapy | Online First

    Radiotherapy in localized prostate cancer: a multicenter analysis evaluating tumor control and late toxicity after brachytherapy and external beam radiotherapy in 1293 patients

    Prostate cancer is an age-related disease [ 1 ]. Being the most common cancer in men [ 1 ] in an aging society, more cases are to be expected and more resources for treatment are required. For localized prostate cancer, 3 different options for …

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