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Hepatocellular Carcinoma 

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  1. Open Access 01-12-2024 | Hepatocellular Carcinoma | OriginalPaper

    Cyclovirobuxine D inhibits hepatocellular carcinoma growth by inducing ferroptosis of hepatocellular carcinoma cells

    Predominantly hepatocellular carcinoma (HCC), liver cancer is the sixth most often diagnosed cancer and the third major cause of cancer mortality globally [ 1 , 2 ]. HCC is closely associated with viral hepatitis, nonalcoholic steatohepatitis …

  2. Open Access 01-12-2024 | Hepatocellular Carcinoma | ReviewPaper

    The regulation of hypoxia-related lncRNAs in hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is still a public health disease with its high prevalence and morbidity. Short of early diagnosis biomarkers and effective therapy, the treatment of HCC patients hasn’t achieved ideal effect. Hypoxia is a hallmark of …

  3. Open Access 01-07-2024 | Hepatocellular Carcinoma | OriginalPaper

    Epigenetic silencing of LDHB promotes hepatocellular carcinoma by remodeling the tumor microenvironment

    Lactate dehydrogenase B (LDHB) reversibly catalyzes the conversion of pyruvate to lactate or lactate to pyruvate and expressed in various malignancies. However, the role of LDHB in modulating immune responses against hepatocellular carcinoma (HCC) …

  4. 07-04-2024 | Hepatocellular Carcinoma | Online First

    Patients undergoing liver resection for non-alcoholic fatty liver disease-related hepatocellular carcinoma and those for viral hepatitis-related hepatocellular carcinoma have similar survival outcomes

    Numerous studies have compared outcomes of liver resection (LR) of patients with non-alcoholic fatty liver disease (NAFLD)-related hepatocellular carcinoma (HCC) to those of patients with non-NAFLD-related HCC. However, results have been …

  5. 14-05-2024 | Hepatocellular Carcinoma | Online First

    Outcome of Transarterial Radioembolization in the Treatment of Hepatocellular Carcinoma: Glass Versus Resin Microsphere

    Transarterial radioembolization using Yttrium-90 ( 90 Y) microspheres is considered a safe and effective treatment option for hepatocellular carcinoma (HCC) [ 1 ]. Though two major randomized controlled trials failed to prove the survival benefit …

  6. 21-03-2024 | Hepatocellular Carcinoma | OriginalPaper

    Imaging and prognostic characterization of fat-containing hepatocellular carcinoma subtypes

    Hepatocellular carcinoma (HCC) is currently the sixth cancer and the third cause of death by cancer worldwide [ 1 ]. According to the 2019 edition of the World Health Organization (WHO) classification of digestive tumors, HCC should be classified …

  7. Open Access 01-12-2024 | Hepatocellular Carcinoma | OriginalPaper

    Prognostic analysis of hepatocellular carcinoma based on cuproptosis -associated lncRNAs

    Hepatocellular carcinoma (HCC) constitutes around 90% of all primary liver cancer instances and ranks as the second leading cause of cancer-related mortality worldwide, with an annual incidence of 850,000 new cases. The principal risk factors for …

  8. Open Access 01-12-2024 | Hepatocellular Carcinoma | ReviewPaper

    Immunosuppressive tumor microenvironment and immunotherapy of hepatocellular carcinoma: current status and prospectives

    Hepatocellular carcinoma (HCC) is a major health concern worldwide, with limited therapeutic options and poor prognosis. In recent years, immunotherapies such as immune checkpoint inhibitors (ICIs) have made great progress in the systemic …

  9. Open Access 01-05-2024 | Hepatocellular Carcinoma | OriginalPaper

    RRP8, associated with immune infiltration, is a prospective therapeutic target in hepatocellular carcinoma

    Globally, 841,000 new cases of HCC are diagnosed each year, and 782,000 deaths are caused by the disease (Villanueva and Longo 2019 ). HCC development is influenced by a number of important factors, including hepatitis B infection, hepatitis C …

  10. Open Access 01-12-2024 | Hepatocellular Carcinoma | OriginalPaper

    Microinvasion in hepatocellular carcinoma: predictive factor and application for definition of clinical target volume for radiotherapy

    Primary liver cancer is one of the most prevalent tumors that seriously threaten human health [ 1 ]. China is a prominent nation of liver cancer, as it encompasses approximately 50% of the worldwide total cases [ 2 ]. Hepatocellular carcinoma (HCC) …

  11. 01-12-2024 | Hepatocellular Carcinoma | OriginalPaper

    Longitudinal analysis of liver transplant candidates for hepatocellular carcinoma in a single center

    Hepatocarcinogenesis results from a permissive microenvironment created by chronic liver disease [ 1 ]. Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, typically develops against a background of chronic liver disease …

  12. 07-05-2024 | Hepatocellular Carcinoma | Online First

    The Prognostic Value of Preoperative Serum Markers and Risk Classification in Patients with Hepatocellular Carcinoma

  13. Open Access 30-04-2024 | Hepatocellular Carcinoma | Online First

    Managing hepatocellular carcinoma across the stages: efficacy and outcomes of stereotactic body radiotherapy

    A retrospective study

    Liver cancer, ranking as the 6th most prevalent malignancy globally and standing as the third leading cause of cancer-related death, is a challenging malignancy and is surpassed only by lung and colorectal cancer [ 1 ]. Hepatocellular carcinoma

  14. Open Access 01-12-2024 | Hepatocellular Carcinoma | OriginalPaper

    Prevalence of metabolic syndrome among patients with hepatocellular carcinoma of different etiologies: a retrospective study

    The most frequent causes of hepatocellular carcinoma (HCC) are chronic infection with hepatitis B or C virus and alcoholic liver disease [ 1 ]. Nevertheless, the most frequent causes of mortality among HCC patients in recent decades have become …

  15. Open Access 13-05-2024 | Hepatocellular Carcinoma | Online First

    Efficacy and safety of robotic versus laparoscopic liver resection for hepatocellular carcinoma: a propensity score-matched retrospective cohort study

    Primary liver cancer (PLC) is the sixth most common cancer worldwide and the third most common cause of cancer death, with hepatocellular carcinoma (HCC) accounting for about 85% of all PLC [ 1 ]. Despite the rapid advancements in medical …

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