Skip to main content

Circulatory Disease

Free for a limited time Parkinson's Disease Case Study

Hypotensive twilight zone in Parkinson’s disease

Almost daily episodes of reduced responsiveness lasting up to an hour, with the patient slumped back in a chair but staying upright, indicated an under-recognised presentation of orthostatic hypertension.

Editor's Choice

Does intestinal permeability have a role in hypertension?

Open Access Hypertension Review

Evidence from animal models supports the presence of intestinal barrier dysfunction in hypertension, but what is the evidence in humans? Could hypertension increase gut permeability, or vice-versa?

How neuroimmunology affects the heart

Open Access Circulatory Disease Review

What is the brain’s involvement in cardiovascular disease pathology? Evidence suggests that neuroimmune mechanisms may play a key role. 

Treating comorbid heart failure and hypertension

Open Access Heart Failure Review

Managing patients with acute or chronic HFpEF and concurrent hypertension is difficult. Make sure you're confident prescribing the optimal drug combination. 

Our tailored content service will keep you up to date…

Receive newsletters curated for the busy specialist by our expert editorial team

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Episode 3: Unravelling resistant hypertension

Why is it so difficult to diagnose and manage?

Resistant hypertension is a difficult to treat and often misunderstood phenomenon that continues to frustrate cardiologists. 

In this episode, Professors Morris Brown and Bryan Williams debate the causes of resistant hypertension and explore novel treatment options.

Prof. Morris Brown
Prof. Bryan Williams

Case Studies

Hypotensive twilight zone in Parkinson’s disease

Free for a limited time Parkinson's Disease Case Study

Almost daily episodes of reduced responsiveness lasting up to an hour, with the patient slumped back in a chair but staying upright, indicated an under-recognised presentation of orthostatic hypertension.

Profound hypotension induced by ICI treatment

A case of extreme hypotension that could have been prevented or mitigated with awareness of the underlying hypothyroidism related to nivolumab treatment.

Unique presentation of memantine overdose

Open Access Medical Side Effect Case Study

Hypertensive urgency and echolalia were the most striking symptoms of memantine overdose in an elderly man with mild dementia and hypertension. Early medication review with caregivers of people with dementia is key.

Current Reviews

Safety and Efficacy of Anti-Hypertensive Medications in Patients with Heart Failure with Preserved Ejection Fraction: A Systematic Review and Meta-analysis

Heart Failure Review article

Approximately 1 in 4 individuals in developing nations suffer from hypertension (HTN), and nearly a third are asymptomatic upon diagnosis [ 1 ]. Chronic elevations in blood pressure results in increased afterload, which in turn can result in …

Posterior Reversible Encephalopathy Syndrome in Children and Adolescents

Hypertension Pediatric Hypertension (C Hanevold, Section Editor)

Severe, acute hypertension may lead to life-threatening end-organ effects in children. The presence of such findings differentiates “hypertensive emergency” from “hypertensive urgency.” Among pediatric patients, the most common manifestations of …

Diet to Stop Hypertension: Should Fats be Included?

Open Access Hypertension Nutrition and Hypertension (T Mori, Section Editor)

The search strategy includes articles published up to March 2024 derived from research involving human subjects, published in English and indexed in MEDLINE (through PubMed), EMBASE, the Cochrane Library, and other selected databases. Key search …

Haemodynamic monitoring during noncardiac surgery: past, present, and future

Open Access Hypotension Review

During surgery, various haemodynamic variables are monitored and optimised to maintain organ perfusion pressure and oxygen delivery – and to eventually improve outcomes. Important haemodynamic variables that provide an understanding of most …

Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
Developed by: Springer Medicine

Further Reading

Relation Between Exposure to Tobacco Smoke Assessed by Serum Cotinine Concentration and Questionnaire Method, and Serum Renalase Concentration—the Importance of the Coexistence of Arterial Hypertension and Other Cardiovascular Diseases

Exposure to tobacco smoke (ETS) is one of the main risk factors for cardiovascular disease (CVD). Renalase is a protein that may play a role in the pathogenesis of CVD. The aim of the study was to assess the relationship between ETS and serum …

First-trimester serum biomarkers in twin pregnancies and adverse obstetric outcomes–a single center cohort study

Open Access Premature Birth Maternal-Fetal Medicine

Twin pregnancies (TwP) carry a higher risk of major obstetrical complications, including preterm birth (PTB), fetal growth restriction (FGR), hypertensive disorders of pregnancy (HDP) [ 1 , 2 ]. PTB is the most prevalent complication in TwP …

Diet to Stop Hypertension: Should Fats be Included?

Open Access Hypertension Nutrition and Hypertension (T Mori, Section Editor)

The search strategy includes articles published up to March 2024 derived from research involving human subjects, published in English and indexed in MEDLINE (through PubMed), EMBASE, the Cochrane Library, and other selected databases. Key search …

Improvement in clinical features of hypercortisolism during osilodrostat treatment: findings from the Phase III LINC 3 trial in Cushing's disease

Open Access Hypertension Original Article

Cushing’s disease, the most common form of endogenous Cushing’s syndrome, is a rare and debilitating condition caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary tumour, resulting in excessive secretion of cortisol from the …

Related topics