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Solid Tumor Genitourinary Cancer

Genitourinary Cancer

Arrhythmia secondary to abiraterone treatment

A man receiving abiraterone for prostate cancer developed severe hypokalemia, which led to polymorphic ventricular tachycardia and cardiac arrest. It is important to consider iatrogenic causes in cases of arrhythmia.

Postoperative pembrolizumab improves OS in high-risk RCC

18-04-2024 Kidney Cancer News

Adjuvant treatment with pembrolizumab is associated with a significant overall survival benefit in individuals with high-risk renal cell carcinoma.

ADCs in cancer: key data for currently approved agents

Open Access Cancer Therapy Review

Delve into the efficacy and safety data for the antibody–drug conjugates currently approved by the US FDA across tumor types such as hematologic, genitourinary, and gynecologic cancers.

Three-phase screening approach promising for prostate cancer

11-04-2024 Prostate Cancer News

The ProScreen trial points to the potential of a single round of prostate cancer screening involving a PSA test, a kallikrein panel, and an MRI scan.

Lymph node dissection in testicular cancer

Open Access Testicular Cancer Review

Retroperitoneal lymph node dissection is a valuable tool in the management of testicular cancer. Gain an understanding of its key role in diagnosis and staging, and beyond.

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine

Case-Based Insights: Oncology and Hematology (Link opens in a new window)


Refresh your knowledge in Oncology and Hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now

Current Reviews

Management of the Devastated Bladder Outlet after Prostate CANCER Treatment

The bladder outlet is the anatomic segment that comprises the bladder neck and posterior urethra (prostatic and membranous urethra). The devastated bladder outlet (DBO) is a clinical entity characterized by refractory, recalcitrant obstruction …

Prostate cancer biomarkers: from early diagnosis to precision treatment

Prostate Cancer REVIEW ARTICLE

Prostate cancer (PCa) is the second most prevalent cancer in men. In 2020, approximately 1,414,259 new cases were reported that accounted for 3,75,324 deaths (Sung et al. in CA 71:209–249, 2021). PCa is often asymptomatic at early stages; hence …

Enhancing prostate MRI expertise: educational strategies for radiologists

The adoption of multiparametric MRI (mpMRI) and the Prostate Imaging Reporting and Data System has significantly changed prostate cancer diagnosis and management. These advancements, alongside novel biomarkers and updated International Society of …

Biparametric MRI in prostate cancer during active surveillance: is it safe?

Open Access Prostate Cancer Invited Review

Active surveillance (AS) is a strategy recommended by the European Association of Urology (EAU) for patients presenting with low or favourable intermediate-risk prostate cancer (PCa) [ 1 ]. AS involves identifying optimal timings for curative …

Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
Developed by: Springer Medicine

Case Studies

Arrhythmia secondary to abiraterone treatment

A man receiving abiraterone for prostate cancer developed severe hypokalemia, which led to polymorphic ventricular tachycardia and cardiac arrest. It is important to consider iatrogenic causes in cases of arrhythmia.

Lung erosion following adjuvant immunotherapy

Open Access Pneumothorax Case Study

Adjuvant pembrolizumab treatment after resection of lung metastases in a patient with renal cell carcinoma may have led to lung erosion that resulted in a pneumothorax.

Progressive encephalomyelitis with rigidity and myoclonus (PERM) associated with urothelial carcinoma

The first reported case of PERM associated with anti-glycine receptor antibodies in a patient with bladder cancer. PERM, a stiff-person syndrome, has paraneoplastic etiology in about 20% of cases.

eLearning | Interviews | Cases (Link opens in a new window)

Multiformat program highlighting evidence-based best practice for the management of metastatic urothelial carcinoma.

Supported by:
  • Pfizer and Merck Healthcare KGaA, Darmstadt, Germany
Developed by: Springer Healthcare IME

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Further Reading

Evaluation of 68Ga-PSMA-11 PET/CT: a Phase 1 clinical study in Japanese patients with primary, recurrent, or suspected recurrent prostate cancer

Open Access Prostate Cancer Original Article

Prostate cancer (PC) has increasing significance: it is the second most frequent cancer diagnosis in patients and the fifth leading cause of cancer death worldwide [ 1 ]. In Japan, the incidence of PC has been growing rapidly over the past decades.

Interpretable multiphasic CT-based radiomic analysis for preoperatively differentiating benign and malignant solid renal tumors: a multicenter study

Open Access Renal Cancer Kidneys, Ureters, Bladder, Retroperitoneum

Renal cancer is the third leading cause of genitourinary cancer death, and its incidence has been increasing over the past decade [ 1 ]. Renal cell carcinoma (RCC) constitutes approximately 70% of all renal cancers; its most common …

Men with metastatic prostate cancer carrying a pathogenic germline variant in breast cancer genes: disclosure of genetic test results to relatives

Open Access Prostate Cancer Original Article

Some patients with metastatic prostate cancer carry a pathogenic germline variant (PV) in a gene, that is mainly associated with an increased risk of breast cancer in women. If they test positive for such a PV, prostate cancer patients are …

Real-World Impact of Upfront Cytoreductive Nephrectomy in Metastatic Non-Clear Cell Renal Cell Carcinoma Treated with First-Line Immunotherapy Combinations or Tyrosine Kinase Inhibitors (A Sub-Analysis from the ARON-1 Retrospective Study)

Open Access Tyrosine Kinase Inhibitors Original Research

Renal cell carcinoma (RCC) represents one of the most prevalent urogenital malignancies with increasing incidence in developed countries [ 1 ]. Clear cell RCC is the predominant histological type, accounting for about 80% of all RCC cases.